Unlocking growth factors to promote

natural bone regeneration

The NMP process unlocks the growth factors naturally found in bone, making them bioavailable.

Advanced Bone

Regeneration Solutions

Induce Oi-9™ bioimplants are 100% allograft products processed with innovative NMP technology, designed to enhance the bioavailability of growth factors for optimal bone regeneration. These bioimplants are available in multiple forms, including fibers and particulates, to accommodate diverse procedural needs and ensure seamless integration into clinical workflows.

Convenient and shelf-stable, Induce Oi-9™ products are sterile and can be stored at ambient temperatures. At the time of use, they can be quickly rehydrated using blood, sterile saline (0.9%), or another isotonic solution, based on the clinician’s preference.

Induce Oi-9™ bioimplants are tissue-based products that meet the criteria for regulation solely under section 361 of the PHS Act and are considered 361 HCT/P. Each product package includes an Instructions for use (IFU) document, which should be reviewed for detailed product information.

Typical Procedures for

Induce Oi-9™ Bioimplants

Induce Oi-9™ bioimplants are designed for versatility, offering effective solutions for

a wide range of bony defect procedures, including:

Socket Preservation

Dental Implant Placement

Sinus Lift

Ridge Augmentation

Trauma Repair

Osteoregeneration

Induce Oi-9™ technology increases the bioavailability of the array of naturally present growth factors supporting the bone forming process.

Osteoregeneration

A precise, multi-faceted process guided by multiple growth factors to support effective healing.

Osteoinduction

**Kohen Y., Shivanna S. and Peel SAF. Evaluation of Natural Matrix Proteins (NMP) Bone Allograft in vitro and in vivo.

MicroCT images of DBM, rhBMP-2 and Induce Oi-9™ implants 28 days post implantation. Grey mass is unmineralized tissue. White areas within the mass are mineralized bone.**

In the gold standard rat muscle pouch model testing for osteoinductive potential,

Induce Oi-9™ bioimplants out performed both standard DBM and rhBMP-2.

DBM

rhBMP-2

Induce Oi-9™

Osteoinduction

The Induce Oi-9™ bioimplant has been shown to form more bone of a better quality than rhBMP-2 in animal studies.

Induce Oi-9™ bioimplants are freeze dried and sterile and should be stored at ambient temperature. To rehydrate and prepare product for use, cover allograft with whole blood, bone marrow aspirate (BMA), Lactated Ringers, normal saline, or other isotonic solution of choice. Please see Instructions For Use (IFU) included with each product for more information.

Storage & Handling

Tissue Procurement

We have partnered with tissue banks accredited by the American Association of Tissue Banks (AATB) to perform donor screening, tissue procurement procedures, and processing of human bone using our proprietary process to prepare our Induce Oi-9™ products.

Please complete the Allograft Tissue Usage form included with each product and return the form to the applicable tissue bank.

INDUCE Oi-9™ FiberMatrix

Product Code	Description	Size
OI9FM0-5	INDUCE Oi-9™ FiberMatrix	0.5cc
OI9FM1-0	INDUCE Oi-9™ FiberMatrix	1.0cc
OI9FM2-5	INDUCE Oi-9™ FiberMatrix	2.5cc

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INDUCE Oi-9™ Micro Particulates

Product Code	Description	Size
OI9MP0-5	INDUCE Oi-9™ Micro Particulates	0.5cc
OI9MP1-0	INDUCE Oi-9™ Micro Particulates	1.0cc
OI9MP2-5	INDUCE Oi-9™ Micro Particulates	2.5cc

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INDUCE Oi-9™ Cancellous

Product Code	Description	Size
OI9CAN0-5	INDUCE Oi-9™ Cancellous	0.5cc
OI9CAN1-0	INDUCE Oi-9™ Cancellous	1.0cc
OI9CAN2-5	INDUCE Oi-9™ Cancellous	2.5c

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